Does a kidney donor need a perfect HLA match?
No — modern immunosuppression means even imperfectly matched transplants succeed.
Donation
HLA matching in kidney transplant
What HLA tissue matching is and why it matters for transplant.
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Short Answer
HLA matching compares tissue markers between donor and recipient. A better match improves long-term graft survival, though modern immunosuppression reduces its importance.
Medical Facts
- HLA markers are inherited tissue proteins.
- Better matching is linked to better long-term outcomes.
Treatment or Donation Options
- Ask your transplant team about your match results.
- Understand that a perfect match is not required for a successful transplant.
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